6. Guidelines for Chlorine Dioxide Intratumoral Injection in Esophageal Cancer
6.1 Indications
6.1.1 Suitable for all stages of esophageal cancer, including cervical, upper, middle, lower, and cardia, particularly for those unable or unwilling to undergo surgery.
6.1.2 Recurrence at the surgical anastomosis site.
6.1.3 Recurrence post-radiotherapy or chemotherapy.
6.1.4 Patients refusing radiotherapy or chemotherapy.
6.1.5 Patients with normal clotting and coagulation profiles.
6.2 Contraindications
6.2.1 Signs of impending perforation, such as ulceration or severe chest pain and fever.
6.2.2 Elderly or frail patients who cannot tolerate endoscopy.
6.2.3 Severe obstruction preventing oral intake.
6.2.4 Cardiorespiratory dysfunction and cachexia.
6.2.5 Active hepatitis B and pulmonary tuberculosis.
6.2.6 PLT < 60×10⁹/L.
6.3 Needles and Auxiliary Equipment
6.3.1 Use endoscopic puncture needles, injectors, endoscope, and bite blocks.
6.4 Pre-Treatment Preparation
6.4.1 Conduct required tests: blood and coagulation profiles, liver function, hepatitis B panel, tumor markers, ultrasound, chest CT, and barium swallow.
6.4.2 Provide consultation, discuss potential complications (fever, pain, bleeding, perforation), and obtain consent.
6.4.3 Fast for 4 hours prior. Administer anisodamine, buclizine, and antifibrinolytics intramuscularly 15 minutes before, and provide esophageal mucosal anesthetic-lubricant gel orally 5-10 minutes before the procedure.
6.5 Procedure
6.5.1 Position the patient on their left side with head slightly forward.
6.5.2 Insert the endoscope, observe and assess the esophageal condition.
6.5.3 If narrowed, inject above the tumor. If passable, observe and inject at multiple points: single-point for tumors ≤4 cm, multi-point for larger tumors, 30% of the tumor volume at each point.
6.5.4 Post-injection, remove the endoscope, observe for 10-15 minutes, then return the patient to the ward.
6.6 Post-Treatment Care
6.6.1 Allow liquid/semi-liquid food 2 hours later.
6.6.2 Administer intravenous anti-infectives and antacids.
6.6.3 Monitor for fever, chest pain, nausea, and vomiting, treating symptoms as necessary.
6.6.4 Conduct routine tests every 3-4 days, including blood and liver/kidney function.
6.6.5 Schedule treatments about a week apart; assess immune function and perform X-ray and CT before discharge.
6.7 Clinical Experience and Considerations
6.7.1 Address bloating and coughing by having the patient sit up; allow liquids 2 hours after analgesics wear off.
6.7.2 For throat discomfort, use lozenges; manage edema with mannitol if needed.
6.7.3 Ensure fasting, anesthetize thoroughly with gel, and administer meds incrementally to prevent inflammation.
6.7.4 Communicate clearly, position correctly, and encourage patient cooperation.
I put a link from here to Dr Makis substack, so, let's see if this treatment gets recognition.
My brother died from this cancer, suffering terribly with his first radiation treatment, burning through his windpipe, making eating and drinking impossible due to anything by mouth going into his lungs. This was followed by butchery to lymph nodes in his neck, leaving him deformed, unable to lift his head up again as it was pulled down and over on the surgery side. He was a pitiful sight. I hope, very much, yours, and others, who have cures are easily available to those that need it. The powers that shouldn't be have always managed to prevent these alternative real cures so they can continue their money making treatments.