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Clinical Reports

Intratumoral Chlorine Dioxide Ablation in a 13-Year-Old Cat With Forelimb Squamous Cell Carcinoma

China’s first feline tumor case in our intratumoral ClO₂ ablation program

Xuewu Liu's avatar
Xuewu Liu
Sep 04, 2026
∙ Paid

Case date: September 4, 2026, Beijing, China | Procedure time: approximately 9:40 PM

A first feline case

On the evening of September 4, 2026, we treated the first cat in our Chinese veterinary intratumoral chlorine dioxide ablation program. The patient was a 13-year-old white domestic cat with a histopathologically confirmed squamous cell carcinoma (SCC) involving the left forelimb.

The lesion measured approximately 3 cm in length and about 0.5 cm in thickness. The cat and owner traveled from Zhangjiakou and arrived at the Beijing veterinary hospital at approximately 8:00 PM. After examination, the veterinary team considered the patient suitable for general anesthesia.

Before treatment

Figure 1 was taken one day before the procedure. Figure 2 shows the lesion after sedation, analgesia, general anesthesia and antiseptic preparation immediately before injection.

Figure 1. The left forelimb SCC one day before treatment.

Figure 2. The tumor after anesthesia and antiseptic preparation, immediately before injection.

The procedure: approximately 2 mL, completed within minutes

After sedation and analgesia, general anesthesia was induced. The needle was advanced in a plane approximately parallel to the lesion, and about 2 mL of chlorine dioxide ablation solution was delivered intratumorally. The injection itself was rapid and the procedural injection phase was completed in less than five minutes.

There was visible oozing from the tumor during injection. Within approximately three minutes after the injection, however, the external appearance of the lesion had already changed substantially: the bleeding had stopped, parts of the surface had become darker or black, and other areas had developed a pale, milky-white appearance.

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